July 2015 News Bulletin: chemicals in textiles; a popcorn problem

July 16, 2015 at 12:35 pm | Posted in News and Science Bulletins | Leave a comment

July 2015 News Bulletin

BPA still a favorite among canned good brands. In a survey of more than 250 brands of canned food, researchers found that more than 44 percent use bisphenol-A lined cans for some or all of their products. With 109 brands not responding or providing enough information, that number could be a lot higher. (EHN)

Chemicals in Your Popcorn? What do a pizza box, a polar bear and you have in common? All carry a kind of industrial toxicant called poly- and perfluoroalkyl substances, or PFASs, that do two things: They make life convenient, and they also appear to increase the risk of cancer. (NYT)

Cotton, cashmere, chemicals – what really goes into making our clothes? As the federal agency responsible for enforcing the Textile Products Identification Act and related laws, the FTC makes sure clothing is accurately labeled with its fabric content. But it turns out, apart from these laws and a few others, there is no overarching U.S. law that regulates or requires listing of materials outside of fabrics that go into producing our clothing. Why does this matter? Because manufacturers use hundreds of substances to produce clothing that don’t show up on clothing labels. And many of these are hazardous to the environment and to human health. (Ensia)

Echa committee recommends BPA restriction in thermal paper. Presence in till receipts presents risk to workers, says Rac. (ChemicalWatch, subscription only)

Everyday plastics plunge men into fertility crisis. Plastics have caused a sharp decline in fertility among men, leaving only one in four with “good” sperm, scientists say. Chemicals called phthalates — found in plastics and products such as shower curtains, car dashboards and cleaning materials — can be breathed in, consumed or absorbed through the skin of pregnant women, inhibiting testosterone production in male foetuses, leading to sons with low sperm counts. (Times, subscription only)

Regulators And Retailers Raise Pressure On Phthalates. Phthalates provide flexibility to vinyl products, but they are also controversial. Concerns—justified or not—have been bubbling up for more than a decade over their potential to disrupt hormones and cause reproductive and developmental effects. As a result, the plasticizer industry is in a state of flux, scrambling to adapt to ever-changing demands from regulators and the marketplace. (Chemical & Engineering News)

July 2015 Science Bulletin #2: EDC mixtures affect mammary gland development and parenting behaviours

July 14, 2015 at 12:35 pm | Posted in News and Science Bulletins | Leave a comment
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July 2015 Science Bulletin #2:
Non-human research

EDCs, mammary gland development | Mixtures of environmentally relevant endocrine disrupting chemicals affect mammary gland development in female and male rats. Estrogenic chemicals are able to alter mammary gland development in female rodents, but little is known on the effects of anti-androgens and mixtures of endocrine disrupting chemicals (EDCs) with dissimilar modes of action. Oestrogens increased mammary outgrowth in prepubertal females and the mRNA level of matrix metalloproteinase-3, which may be a potential biomarker for increased outgrowth. Mixtures of EDCs gave rise to ductal hyperplasia in adult males. Adult female mammary glands of the TotalMix group showed morphological changes possibly reflecting increased prolactin levels.

EDCs, parenting behaviours | Disruption of Parenting Behaviors in California Mice, a Monogamous Rodent Species, by Endocrine Disrupting Chemicals. Females exposed to either BPA or EE spent less time nursing, grooming and being associated with their pups than controls, although there was little consequence on their weight gain. Care of pups by males was less affected by exposure to BPA and EE, but control, non-exposed females appeared able to “sense” a male partner previously exposed to either compound and, as a consequence, reduced their own parental investment in offspring from such pairings.

BPS, heart rhythm | Rapid Responses and Mechanism of Action for Low-Dose Bisphenol S on ex Vivo Rat Hearts and Isolated Myocytes: Evidence of Female-Specific Proarrhythmic Effects. Rapid exposure to low-dose BPS showed proarrhythmic impact on female rat hearts; these effects at the organ, cellular, and molecular levels are remarkably similar to those reported for BPA. Evaluation of the bioactivity and safety of BPS and other BPA analogs is necessary before they are used as BPA alternatives in consumer products.

July 2015 Science Bulletin #1: Systematic review of EDCs and T2 diabetes; PFOS and male genital abnormalities; and more

July 13, 2015 at 2:49 pm | Posted in News and Science Bulletins | Leave a comment
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July 2015 Science Bulletin #1:
Human Research

EDCs, T2 diabetes | Endocrine-Disrupting Chemicals, Risk of Type 2 Diabetes, and Diabetes-Related Metabolic Traits: A Systematic Review and Meta-analysis. Persistent and non-persistent EDCs may affect the risk of T2D. There is an urgent need for further investigation of EDCs, especially non-persistent ones, and T2D risk in large prospective studies.

Pesticides, ADHD | Association of pyrethroid pesticide exposure with attention-deficit/hyperactivity disorder in a nationally representative sample of U.S. children. Study finding an association between increasing pyrethroid pesticide exposure and ADHD which may be stronger for hyperactive-impulsive symptoms compared to inattention and in boys compared to girls. Given the growing use of pyrethroid pesticides, these results may be of considerable public health import.

Solvents, breast cancer | Occupational exposure to solvents and risk of breast cancer. This study suggests that there may be an association between occupational exposure to aliphatic and aromatic solvents and the risk of breast cancer at the low levels of exposure experienced by women in this study.

PFCs, genital abnormalities | Perfluorooctane Sulfonate Concentrations in Amniotic Fluid, Biomarkers of Fetal Leydig Cell Function, and Cryptorchidism and Hypospadias in Danish Boys. Environmental PFOS exposure was associated with steroid hormone and INSL3 concentrations in amniotic fluid, but was not associated with cryptorchidism or hypospadias in our study population. Additional studies are needed to determine whether associations with fetal hormone levels may have long-term implications for reproductive health.

POPs, breast cancer | DDT Exposure in Utero and Breast Cancer. This prospective human study links measured DDT exposure in utero to risk of breast cancer. Experimental studies are essential to confirm results and discover causal mechanisms. Findings support classification of DDT as an endocrine disruptor, a predictor of breast cancer, and a marker of high risk. See news coverage here (Washington Post).

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